Lithium, Serum

From Taranaki Lab Manual
Tests:Lithium, Serum
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Overview

Department Biochemistry
Test Code LI
Synonyms LiCO3

Lithicarb

Priadel

Availability Monday - Sunday, testing routinely available out of hours
Turnaround Time 1 – 5 hrs
Stability – Add test 5 days

Specimen Requirements

Patient Preparation Sample should be taken as a trough, ideally 12 hours post dose 
Specimen Serum
Preferred Plain Yellow top or Red-Top tube
Acceptable
Unacceptable Li-Hep Green-top tubes
Specimen Transportation
Paediatric Requirements 1 mL Red-Top tube

Aliquot Requirements

Sample Serum
Preferred Volume 0.5 mL
Minimum Volume >0.25 mL
Aliquot Transportation

Clinical Information

Reference Intervals Therapeutic Range 0.4 - 1.2 mmol/L 

For prophylaxis, a concentration of 0.4 - 0.8 mmol/L may be optimal. A range of 0.8 - 1.2 mmol/L is suggested for acute mania. Toxicity is common above 1.2 mmol/L and may be severe. Lithium clearance is reduced with renal impairment.

Test Method Abbott Alinity c series analyser using Abbott reagents.

Colorimetric assay.

Advanced Notice

Comments

Please supply last dose time and date if available 
Owner Clair Crossley (Crossley1)
Last reviewed 30.01.2026
Next review 30.01.2027 (OK)