Tests:Valproic Acid: Difference between revisions

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Tests:Valproic Acid
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Created page with "{{DISPLAYTITLE: Valproic Acid}} Full Test List Biochemistry Tests {| class="wikitable" ! colspan="2" | === ''Overview'' === |- |Department |Biochemistry |- |Test Code | |- |Synonyms |Valproate Sodium Valproate Epilim Valpro |- |Turnaround Time |1 – 5 hrs |- ! colspan="2" | === Specimen Requirements === |- |Specimen Type |Plasma Serum |- |Specimen Transportation | |- |Preferred |6 mL Plain <span style="background:#e30022"> Red-Top</spa..."
 
Updated method Alinity
 
(3 intermediate revisions by 2 users not shown)
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{| class="wikitable"
{| class="wikitable"
! colspan="2" |
! colspan="2" |
=== ''Overview'' ===
== Overview ==
|-
|-
|Department  
|Department  
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Valpro  
Valpro  
|-
|Availability
|Monday - Sunday, testing routinely available out of hours
|-
|-
|Turnaround Time  
|Turnaround Time  
|1 – 5 hrs  
|1 – 5 hrs  
|-
|Stability – Add test
|
|-
|-
! colspan="2" |
! colspan="2" |
=== Specimen Requirements ===
== Specimen Requirements ==
|-
|-
|Specimen Type
|Specimen  
|Plasma
|Plasma


Serum
Serum
|-
|Specimen Transportation
|
|-
|-
|Preferred  
|Preferred  
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|6 mL Li-Hep <span style="background:#3cb371"> Green-Top </span>  
|6 mL Li-Hep <span style="background:#3cb371"> Green-Top </span>  
|-
|-
|Pediatric Requirements    
|Unacceptable
|
|-
|Specimen Transportation
|
|-
|Paediatric Requirements    
|600 μL <span style="background:#99e6b3"> Li-Hep Microtainer </span> 
|600 μL <span style="background:#99e6b3"> Li-Hep Microtainer </span> 
|-
|-
! colspan="2" |
! colspan="2" |
=== ''Aliquot Requirements'' ===
== Aliquot Requirements ==
|-
|-
|Sample Type
|Sample  
|Plasma  
|Plasma  


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|-
|-
|Aliquot Transportation  
|Aliquot Transportation  
|
|-
|Stability – Add test
|
|
|-
|-
! colspan="2" |
! colspan="2" |
=== ''Clinical Information'' ===
== Clinical Information ==
|-
|-
|Reference Intervals  
|Reference Intervals  
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|-
|-
|Test Method  
|Test Method  
|Abbott Alinity Ci, Particle-enhanced turbidimetric inhibition immunoassay (PETINIA).  
|Abbott Alinity c series analyser using Abbott reagents. Particle-enhanced turbidimetric inhibition immunoassay (PETINIA).  
|-
|-
|Advanced Notice  
|Advanced Notice  
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|-
|-
! colspan="2" |
! colspan="2" |
=== ''Comments'' ===
== Comments ==
|-
|-
| colspan="2" |With patient at steady state, samples should be collected immediately before next dose (trough level).  
| colspan="2" |With patient at steady state, samples should be collected immediately before next dose (trough level).  
|}
|}
{{DocMeta
| owner = Crossley1
| review_ping =
}}

Latest revision as of 21:10, 23 September 2026

Overview

Department Biochemistry
Test Code
Synonyms Valproate

Sodium Valproate

Epilim

Valpro

Availability Monday - Sunday, testing routinely available out of hours
Turnaround Time 1 – 5 hrs
Stability – Add test

Specimen Requirements

Specimen Plasma

Serum

Preferred 6 mL Plain Red-Top
Acceptable 6 mL Li-Hep Green-Top
Unacceptable
Specimen Transportation
Paediatric Requirements   600 μL Li-Hep Microtainer

Aliquot Requirements

Sample Plasma

Serum

Preferred Volume 1 mL
Minimum Volume 0.1 mL
Aliquot Transportation

Clinical Information

Reference Intervals 350 – 700 umol/L.

Although values <300 umol/L are generally ineffective and values >700 are more likely to be toxic, the concentration does not correlate well with efficacy/toxicity.  

Dose adjustment should be based primarily on clinical indicators

Test Method Abbott Alinity c series analyser using Abbott reagents. Particle-enhanced turbidimetric inhibition immunoassay (PETINIA).
Advanced Notice
Patient Preparation With patient at steady state, samples should be collected immediately before next dose (trough level).

Comments

With patient at steady state, samples should be collected immediately before next dose (trough level).
Owner Clair Crossley (Crossley1)
Last reviewed 23.09.2026
Next review 23.09.2027 (OK)