Tobramycin, Serum

Overview
Department	Biochemistry
Test Code	TOBR
Synonyms	Nebcin
Test Availability	Monday - Sunday, testing routinely available out of hours
Turnaround Time	1 – 4hrs
Stability – Add test
Specimen Requirements
Specimen Type	Serum Plasma
Preferred	6 mL Red-Top
Acceptable	6 mL Li-Hep Green-Top
Unacceptable
Specimen Transportation
Paediatric Requirements	600uL Li-Hep Microtainer
Aliquot Requirements
Sample Type	Serum Li-Hep Plasma
Preferred Volume	1 mL
Minimum Volume	0.2 mL
Aliquot Transportation
Clinical Information
Reference Intervals	Trough level: 0 - 2 mg/L   Peak level: 5 - 10 mg/L
Test Method	Abbott Alinity Ci using Abbott reagents
Advanced Notice	Please notify the laboratory in advance of any scheduled testing – extn 7881
Patient Preparation	Please supply last dosage details (Start time, date, and dosage amount)
Comments
Telephone communication about impending requests will greatly facilitate rapid results.   Once daily dosing is recommended using a target area-under-the-concentration (AUC) curve. Contact the ward Pharmacist. Aminoglycoside clearance is reduced with renal impairment.