Tobramycin, Serum

Overview
Department	Biochemistry
Test Code	TOBR
Synonyms	Nebcin
Availability	Monday - Sunday, testing routinely available out of hours
Turnaround Time	1 – 4hrs
Stability – Add test	24 hours
Specimen Requirements
Patient Preparation	Please supply last dosage details (Start time, date, and dosage amount)
Specimen	Serum Plasma
Preferred	Li-Hep Green-Top tube
Acceptable	Red-Top or Yellow-Top tube
Unacceptable
Specimen Transportation
Paediatric Requirements	600uL Li-Hep Microtainer
Aliquot Requirements
Sample	Plasma Serum
Preferred Volume	0.5 mL
Minimum Volume	0.2 mL
Aliquot Transportation
Clinical Information
Reference Intervals	Trough level: 0 - 2 mg/L   Peak level: 5 - 10 mg/L
Test Method	Abbott Alinity c series analyser using Abbott reagents. Particle-enhanced turbidimetric inhibition immunoassay (PETINIA)
Advanced Notice	Please notify the laboratory in advance of any scheduled testing – extn 7881
Comments
Telephone communication about impending requests will greatly facilitate rapid results.   Once daily dosing is recommended using a target area-under-the-concentration (AUC) curve. Contact the ward Pharmacist. Aminoglycoside clearance is reduced with renal impairment.

Owner	Clair Crossley (Crossley1)
Last reviewed	30.01.2026
Next review	30.01.2027 (OK)