Tests:Creatinine Plasma: Difference between revisions
m Bulk update DocMeta owner to Crossley1 |
Updated method change (enzymatic) and changes in reference intervals |
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[[Category:Tests]] | [[Category:Tests]] | ||
[[Category:Biochemistry]] | [[Category:Biochemistry]] | ||
[[Category:Hawera]] | |||
{| class="wikitable" | {| class="wikitable" | ||
! colspan="2" | | ! colspan="2" | | ||
| Line 15: | Line 16: | ||
|CRN, plasma | |CRN, plasma | ||
|- | |- | ||
|Availability | |Base Lab Availability | ||
|Monday - Sunday, testing routinely available out of hours | |Monday - Sunday, testing routinely available out of hours | ||
|- | |||
|Hawera Lab Availability | |||
|Monday - Friday, 8am to 4 30pm | |||
|- | |- | ||
|Turnaround Time | |Turnaround Time | ||
| Line 69: | Line 73: | ||
| | | | ||
|- | |- | ||
|0 - 1 | |0 - < 1 week | ||
| | |< 90 | ||
|- | |- | ||
| | |1 week - < 4 weeks | ||
| | |< 50 | ||
|- | |- | ||
| | |4 weeks - < 2 years | ||
| | | < 40 | ||
|- | |- | ||
| | |2 years - < 6 years | ||
| | |< 50 | ||
|- | |- | ||
| | | 6 years - < 12 years | ||
| | |< 65 | ||
|- | |- | ||
| | |12 years to < 15 years | ||
| | |< 80 | ||
|- | |- | ||
|Male >15yr + Adult | |Male >15yr + Adult | ||
| Line 122: | Line 126: | ||
|- | |- | ||
| Test Method | | Test Method | ||
| | |Methodology: Enzymatic Creatinine assay using Abbott reagent on the Alinity c series (Base) and Architect c8000 (Hawera) analyser. | ||
eGFR routinely reported on all valid samples (patients < 16 years excluded). Calculated using the plasma creatinine and CKD-EPI calculation. | |||
eGFR routinely reported on all valid samples. Calculated using the plasma creatinine and | |||
|- | |- | ||
|Advanced Notice | |Advanced Notice | ||
Latest revision as of 11:34, 14 January 2026
Overview | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Department | Biochemistry | ||||||||||||||||||
| Test Code | PCRN | ||||||||||||||||||
| Synonyms | CRN, plasma | ||||||||||||||||||
| Base Lab Availability | Monday - Sunday, testing routinely available out of hours | ||||||||||||||||||
| Hawera Lab Availability | Monday - Friday, 8am to 4 30pm | ||||||||||||||||||
| Turnaround Time | 1 hour urgent - 2 hours routine | ||||||||||||||||||
| Stability – Add test | 24 hours | ||||||||||||||||||
Specimen Requirements | |||||||||||||||||||
| Specimen | Serum
Plasma | ||||||||||||||||||
| Preferred | 6 mL Plain Red-Top | ||||||||||||||||||
| Acceptable | 4 mL Li-Heparin Green-Top | ||||||||||||||||||
| Specimen Transportation | |||||||||||||||||||
| Pediatric Requirements | 600 µL Li-Heparin Microtainer | ||||||||||||||||||
Aliquot Requirements | |||||||||||||||||||
| Sample | Plasma
Serum | ||||||||||||||||||
| Preferred Volume | 100 µL | ||||||||||||||||||
| Minimum Volume | |||||||||||||||||||
| Aliquot Transportation | |||||||||||||||||||
Clinical Information | |||||||||||||||||||
| Reference Intervals |
CKD-EPI calculation for eGFR Reference range: 80 - 120 mL/min/1.73 m2
Crn ≤62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-0.329 x [0.993] Age. Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age. Male Crn ≤80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]-0.411 x [0.993] Age. Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age. Children < 16 years- no calculation done
Estimated GFR is only reliable under steady state conditions (stable Creatinine >4 days). Caution should be used in interpretation in non-Caucasians, extremes of body weight, pregnancy, oedematous subjects, low Creatinine (<0.06mmol/L) and other complex cases. GFR declines by 1 ml/min/year over 40 years. | ||||||||||||||||||
| Test Method | Methodology: Enzymatic Creatinine assay using Abbott reagent on the Alinity c series (Base) and Architect c8000 (Hawera) analyser.
eGFR routinely reported on all valid samples (patients < 16 years excluded). Calculated using the plasma creatinine and CKD-EPI calculation. | ||||||||||||||||||
| Advanced Notice | Not required | ||||||||||||||||||
| Patient Preparation | Not required | ||||||||||||||||||
Comments | |||||||||||||||||||
| Owner | Clair Crossley (Crossley1) |
|---|---|
| Last reviewed | 14.01.2026 |
| Next review | 14.01.2027 (OK) |