Tests:Creatinine Plasma: Difference between revisions

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Tests:Creatinine Plasma
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Updated method change (enzymatic) and changes in reference intervals
 
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|CRN, plasma
|CRN, plasma
|-
|-
|Availability
|Base Lab Availability
|Monday - Sunday, testing routinely available out of hours
|Monday - Sunday, testing routinely available out of hours
|-
|Hawera Lab Availability
|Monday - Friday, 8am to 4 30pm
|-
|-
|Turnaround Time
|Turnaround Time
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|
|
|-
|-
|0 - 1 mth
|0 - < 1 week
|20 - 60   
|< 90
|-
|-
|>1 mth - 2  yr
|1 week - < 4 weeks
|20 - 50
|< 50
|-
|-
|>2 yrs - 4  yrs ,
|4 weeks - < 2 years
| 20 - 60
| < 40
|-
|-
|>4 yrs - 6yrs
|2 years - < 6 years
|25 - 65
|< 50
|-
|-
| >6 yrs - 10yrs
| 6 years - < 12 years
|25 - 70
|< 65
|-
|-
|>10 yrs -  15 yrs
|12 years to < 15 years
|40 -  80
|< 80
|-
|-
|Male >15yr  + Adult
|Male >15yr  + Adult
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|-
|-
| Test Method
| Test Method
|Classical Jaffe Reaction using Abbott reagents on the Abbott ci8200 analyser. 
|Methodology: Enzymatic Creatinine assay using Abbott reagent on the Alinity c series (Base) and Architect c8000 (Hawera) analyser.
 
eGFR routinely reported on all valid samples (patients < 16 years excluded).  Calculated using the plasma creatinine and CKD-EPI calculation.
eGFR routinely reported on all valid samples.  Calculated using the plasma creatinine and CKD-EPI calculation.
|-
|-
|Advanced Notice
|Advanced Notice

Latest revision as of 11:34, 14 January 2026

Overview

Department Biochemistry 
Test Code PCRN
Synonyms CRN, plasma
Base Lab Availability Monday - Sunday, testing routinely available out of hours
Hawera Lab Availability Monday - Friday, 8am to 4 30pm
Turnaround Time 1 hour urgent - 2 hours routine 
Stability – Add test 24 hours

Specimen Requirements

Specimen Serum

Plasma

Preferred 6 mL Plain Red-Top
Acceptable 4 mL Li-Heparin Green-Top  
Specimen Transportation
Pediatric Requirements 600 µL   Li-Heparin Microtainer

Aliquot Requirements

Sample Plasma

Serum

Preferred Volume 100 µL
Minimum Volume
Aliquot Transportation

Clinical Information

Reference Intervals  
Creatinine µmol/L
0 - < 1 week < 90
1 week - < 4 weeks < 50
4 weeks - < 2 years < 40
2 years - < 6 years < 50
6 years - < 12 years < 65
12 years to < 15 years < 80
Male >15yr + Adult 50 -  110  
Female >15 yr + Adult 45 - 90

CKD-EPI calculation for eGFR

Reference range: 80 - 120 mL/min/1.73 m2


Female

Crn ≤62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-0.329 x [0.993] Age.

Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.

Male 

Crn ≤80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]-0.411 x [0.993] Age.

Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.

Children < 16 years- no calculation done


Interpretation

Estimated GFR is only reliable under steady state conditions (stable Creatinine >4 days).

Caution should be used in interpretation in non-Caucasians, extremes of body weight, pregnancy, oedematous subjects, low Creatinine (<0.06mmol/L) and other complex cases.

GFR declines by 1 ml/min/year over 40 years.

Test Method Methodology: Enzymatic Creatinine assay using Abbott reagent on the Alinity c series (Base) and Architect c8000 (Hawera) analyser.

eGFR routinely reported on all valid samples (patients < 16 years excluded).  Calculated using the plasma creatinine and CKD-EPI calculation.

Advanced Notice Not required  
Patient Preparation Not required

Comments

Owner Clair Crossley (Crossley1)
Last reviewed 14.01.2026
Next review 14.01.2027 (OK)