Tests:Creatinine Plasma: Difference between revisions

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Tests:Creatinine Plasma
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Created page with "{{DISPLAYTITLE: Creatinine, Plasma}} Full Test List Biochemistry Tests {| class="wikitable" ! colspan="2" | ===''Overview''=== |- |Department |Biochemistry  |- |Test Code |PCRN |- |Synonyms |CRN, plasma |- |Turnaround Time |1 hour urgent - 2 hours routine  |- |Stability – Add test |24 Hours |- ! colspan="2" | ===''Specimen Requirements''=== |- |Specimen Type |Serum Plasma |- |Specimen Transportation | |- |Preferred |6 mL Plain <span style="background:#e..."
 
Updated method change (enzymatic) and changes in reference intervals
 
(5 intermediate revisions by 2 users not shown)
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[[Category:Tests]]
[[Category:Tests]]
[[Category:Biochemistry]]  
[[Category:Biochemistry]]  
[[Category:Hawera]]
{| class="wikitable"
{| class="wikitable"
! colspan="2" |
! colspan="2" |
===''Overview''===
==Overview==
|-
|-
|Department
|Department
|Biochemistry 
|Biochemistry 
|-
|-
|Test Code
|Test Code  
|PCRN
|PCRN
|-
|-
|Synonyms
|Synonyms
|CRN, plasma
|CRN, plasma
|-
|Base Lab Availability
|Monday - Sunday, testing routinely available out of hours
|-
|Hawera Lab Availability
|Monday - Friday, 8am to 4 30pm
|-
|-
|Turnaround Time
|Turnaround Time
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|-
|-
|Stability – Add test
|Stability – Add test
|24 Hours
|24 hours
|-
|-
! colspan="2" |
! colspan="2" |
===''Specimen Requirements''===
==Specimen Requirements==
|-
|-
|Specimen Type
|Specimen  
|Serum
|Serum


Plasma
Plasma
|-
|Specimen Transportation
|
|-
|-
|Preferred
|Preferred
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|Acceptable
|Acceptable
|4 mL Li-Heparin <span style="background:#3cb371"> Green-Top </span>   
|4 mL Li-Heparin <span style="background:#3cb371"> Green-Top </span>   
|-
|Specimen Transportation
|
|-
|-
|Pediatric Requirements
|Pediatric Requirements
|<span style="background:#99e6b3"> Li-Hep Microtainer </span> microtainer tube 600 µL  
|600 µL  <span style="background:#99e6b3"> Li-Heparin Microtainer </span>
|-
|-
! colspan="2" |
! colspan="2" |
===''Aliquot Requirements''===
==Aliquot Requirements ==
|-
|-
|Sample Type
|Sample  
|Plasma  
| Plasma  
Serum
Serum
|-
|Preferred Volume
|100 µL
|-
|-
|Minimum Volume
|Minimum Volume
|100 µL
|
|-
|-
|Aliquot Transportation
|Aliquot Transportation
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|-
|-
! colspan="2" |
! colspan="2" |
===''Clinical Information''===
==Clinical Information==
|-
|-
|Reference Intervals
|Reference Intervals  
|   
|   
{| class="wikitable"
{| class="wikitable"
|Creatinine µmol/L
| Creatinine µmol/L
|
|
|-
|-
|0 - 1 mth
|0 - < 1 week
|20 - 60   
|< 90
|-
|-
|>1 mth - 2  yr
|1 week - < 4 weeks
|20 - 50
|< 50
|-
|-
|>2 yrs - 4  yrs ,
|4 weeks - < 2 years
|20 - 60
| < 40
|-
|-
|>4 yrs - 6yrs
|2 years - < 6 years
|25 - 65
|< 50
|-
|-
|>6 yrs - 10yrs
| 6 years - < 12 years
|25 - 70
|< 65
|-
|-
|>10 yrs -  15 yrs
|12 years to < 15 years
|40 -  80
|< 80
|-
|-
|Male >15yr  + Adult
|Male >15yr  + Adult
|50 -  110    
|50 -  110  
|-
|-
|Female >15 yr + Adult
| Female >15 yr + Adult
|45 - 90
|45 - 90
|}
|}
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Reference range: 80 - 120 mL/min/1.73 m2  
Reference range: 80 - 120 mL/min/1.73 m2  


'''''Female'''''  
'''''Female'''''  
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Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.  
Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.  


'''''Male'''''   
'''''Male'''''   
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Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.  
Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.  


''<br />Children < 16 years- no calculation done''  
'''''Children''' < 16 years- no calculation done''  


'''''Interpretation'''''  
'''''Interpretation'''''  
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GFR declines by 1 ml/min/year over 40 years.
GFR declines by 1 ml/min/year over 40 years.
|-
|-
|Test Method
| Test Method
|Classical Jaffe Reaction using Abbott reagents on the Abbott ci8200 analyser. 
|Methodology: Enzymatic Creatinine assay using Abbott reagent on the Alinity c series (Base) and Architect c8000 (Hawera) analyser.
 
eGFR routinely reported on all valid samples (patients < 16 years excluded).  Calculated using the plasma creatinine and CKD-EPI calculation.
eGFR routinely reported on all valid samples.  Calculated using the plasma creatinine and CKD-EPI calculation.
|-
|-
|Advanced Notice
|Advanced Notice
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|-
|-
! colspan="2" |
! colspan="2" |
===''Comments''===
==Comments==
|-
|-
| colspan="2" |
| colspan="2" |
|}
|}
{{DocMeta
| owner = Crossley1
| review_ping =
}}

Latest revision as of 11:34, 14 January 2026

Overview

Department Biochemistry 
Test Code PCRN
Synonyms CRN, plasma
Base Lab Availability Monday - Sunday, testing routinely available out of hours
Hawera Lab Availability Monday - Friday, 8am to 4 30pm
Turnaround Time 1 hour urgent - 2 hours routine 
Stability – Add test 24 hours

Specimen Requirements

Specimen Serum

Plasma

Preferred 6 mL Plain Red-Top
Acceptable 4 mL Li-Heparin Green-Top  
Specimen Transportation
Pediatric Requirements 600 µL   Li-Heparin Microtainer

Aliquot Requirements

Sample Plasma

Serum

Preferred Volume 100 µL
Minimum Volume
Aliquot Transportation

Clinical Information

Reference Intervals  
Creatinine µmol/L
0 - < 1 week < 90
1 week - < 4 weeks < 50
4 weeks - < 2 years < 40
2 years - < 6 years < 50
6 years - < 12 years < 65
12 years to < 15 years < 80
Male >15yr + Adult 50 -  110  
Female >15 yr + Adult 45 - 90

CKD-EPI calculation for eGFR

Reference range: 80 - 120 mL/min/1.73 m2


Female

Crn ≤62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-0.329 x [0.993] Age.

Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.

Male 

Crn ≤80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]-0.411 x [0.993] Age.

Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.

Children < 16 years- no calculation done


Interpretation

Estimated GFR is only reliable under steady state conditions (stable Creatinine >4 days).

Caution should be used in interpretation in non-Caucasians, extremes of body weight, pregnancy, oedematous subjects, low Creatinine (<0.06mmol/L) and other complex cases.

GFR declines by 1 ml/min/year over 40 years.

Test Method Methodology: Enzymatic Creatinine assay using Abbott reagent on the Alinity c series (Base) and Architect c8000 (Hawera) analyser.

eGFR routinely reported on all valid samples (patients < 16 years excluded).  Calculated using the plasma creatinine and CKD-EPI calculation.

Advanced Notice Not required  
Patient Preparation Not required

Comments

Owner Clair Crossley (Crossley1)
Last reviewed 14.01.2026
Next review 14.01.2027 (OK)
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