Tests:Digoxin, Plasma: Difference between revisions

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Created page with "{{DISPLAYTITLE: Digoxin, Plasma}} Full Test List Biochemistry Tests {| class="wikitable" ! colspan="2" | ===''Overview''=== |- |Department |Biochemistry |- |Test Code |DIG |- |Synonyms |Digitalis  |- |Turnaround Time |1 – 5hrs  |- |Stability – Add test |8 hours |- ! colspan="2" | ===''Specimen Requirements''=== |- |Specimen Type |Serum Plasma |- |Specimen Transportation | |- |Preferred |6 mL <span style="background:#e30022"> Red-Top</span> |- |Accepta..."
 
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{| class="wikitable"
{| class="wikitable"
! colspan="2" |
! colspan="2" |
===''Overview''===
== Overview ==
|-
|-
|Department
|Department
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|Synonyms
|Synonyms
|Digitalis 
|Digitalis 
|-
|Test Availability
|Monday - Sunday, testing routinely available out of hours
|-
|-
|Turnaround Time
|Turnaround Time
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|-
|-
! colspan="2" |
! colspan="2" |
===''Specimen Requirements''===
== Specimen Requirements ==
|-
|-
|Specimen Type
|Specimen Type
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|6 mL Li-Hep <span style="background:#3cb371"> Green-Top </span>
|6 mL Li-Hep <span style="background:#3cb371"> Green-Top </span>
|-
|-
|Pediatric Requirements
|Unacceptable
|<span style="background:#99e6b3"> Li-Hep Microtainer </span>
|
|-
|Paediatric Requirements
|<span style="background:#99e6b3"> Li-Heparin Microtainer </span>
|-
|-
! colspan="2" |
! colspan="2" |
=== ''Aliquot Requirements'' ===
== Aliquot Requirements ==
|-
|-
|Sample Type
|Sample Type
|Serum
|Serum
Plasma
Plasma
|-
|Preferred Volume
|500 µL 
|-
|-
|Minimum Volume
|Minimum Volume
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|-
! colspan="2" |
! colspan="2" |
===''Clinical Information''===
== Clinical Information ==
|-
|-
|Reference Intervals
|Reference Intervals
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|-
|-
! colspan="2" |
! colspan="2" |
===''Comments''===
== Comments ==
|-
|-
| colspan="2" |Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay.  
| colspan="2" |Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay.  

Revision as of 13:24, 14 March 2025

Overview

Department Biochemistry
Test Code DIG
Synonyms Digitalis 
Test Availability Monday - Sunday, testing routinely available out of hours
Turnaround Time 1 – 5hrs 
Stability – Add test 8 hours

Specimen Requirements

Specimen Type Serum

Plasma

Specimen Transportation
Preferred 6 mL Red-Top
Acceptable 6 mL Li-Hep Green-Top
Unacceptable
Paediatric Requirements Li-Heparin Microtainer

Aliquot Requirements

Sample Type Serum

Plasma

Preferred Volume 500 µL 
Minimum Volume 200 µL 
Aliquot Transportation

Clinical Information

Reference Intervals Range 0.6 - 2.0 nmol/L

Toxic levels >2.0 nmol/L 

Test Method Abbott Alinity Ci, Particle-enhanced turbidimetric inhibition immunoassay (PETINIA) 
Advanced Notice Not required 
Patient Preparation Samples are best taken at the trough, just before the next dose, or at least 8-12 hours post-dose, to avoid falsely high results due to delayed drug distribution after the dose. 

Comments

Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay.

Heterophilic antibodies have been shown to interact with immunoglobulin reagents in some immunoassay systems.