Tests:Bordetella Pertussis PCR: Difference between revisions

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Tests:Bordetella Pertussis PCR
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Added add-on stability information.
 
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|Synonyms
|Synonyms
|Bordetella pertussis PCR
|Bordetella pertussis PCR
whooping cough PCR  
Whooping cough PCR  
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|-
|Availability
|Availability
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|-
|Stability - Add test
|Stability - Add test
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|Add-ons can be made if an appropriate sample has already been received for other PCR testing within one week of specimen collection.
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== Comments ==
== Comments ==
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| colspan="2" |Influenza A/B and RSV, SAR-CoV-2 and Full Respiratory  Multiplex may be carried out on the same nasopharyngeal swab.
| colspan="2" |Influenza A/B and RSV, SARS-CoV-2 and Full Respiratory  Multiplex may be carried out on the same nasopharyngeal swab.


Please note: Testing of the full respiratory multiplex  assay does not carry the same turnaround times of the Influenza A/B, RSV and  SARS-CoV-2 test(s) as the sample is forwarded to a reference laboratory.   
Please note: Testing of the full respiratory multiplex  assay does not carry the same turnaround times of the Influenza A/B, RSV and  SARS-CoV-2 test(s) as the sample is forwarded to a reference laboratory.   

Latest revision as of 07:35, 24 December 2025


Overview

Department Microbiology - Molecular
Test Code BPCR
Synonyms Bordetella pertussis PCR

Whooping cough PCR

Availability Monday - Friday

8 am - 4 pm

Turnaround Time 72 hours
Stability - Add test Add-ons can be made if an appropriate sample has already been received for other PCR testing within one week of specimen collection.

Specimen Requirements

Specimen Type
Specimen Transportation ASAP to Laboratory

If there is a delay in getting sample to the laboratory, please store sample chilled (2 - 8 degrees Celsius)

Preferred Nasopharyngeal, Pernasal swab in Universal / Virus transport medium (UTM/VTM) 
Acceptable
Unacceptable Leaking samples

Unlabelled samples

Paediatric Requirements Nasopharyngeal, Pernasal swab in UTM/VTM 

Aliquot Requirements

Sample Type
Preferred Volume
Minimum Volume
Aliquot Transportation

Clinical Information

Diagnostic use/ Indications Pertussis, also known as whopping cough, is a highly contagious respiratory illness caused by a Gram-negative coccobacillus Bordetella pertussis.

Pertussis is a Section B Notifiable Infectious Diseases Under the Health Act 1956.

Nucleic acid detection after PCR amplification is more sensitive than culture.

During the first 3 weeks of cough PCR sensitivity for detection of B. pertussis is high but drops substantially thereafter.

For optimal assay sensitivity specimens should be taken from the posterior nasopharynx.

Other species of the genus B. parapertussis and B. holmesii are known to exhibit clinical manifestations of respiratory infection similar to a pertussis-like disease,

however these are not notifiable.  

Reference Intervals Results reported as DETECTED or NOT Detected for 
  • Bordetella pertussis
  • Bordetella parapertussis
  • Bordetella holmesii
Test Method Real-time PCR for the qualitative detection and differentiation of DNA from Bordetella pertussis, Bordetella parapertussis and/or Bordetella holmesii. 
Advanced Notice Not required 
Patient Preparation Not required

Comments

Influenza A/B and RSV, SARS-CoV-2 and Full Respiratory Multiplex may be carried out on the same nasopharyngeal swab.

Please note: Testing of the full respiratory multiplex assay does not carry the same turnaround times of the Influenza A/B, RSV and SARS-CoV-2 test(s) as the sample is forwarded to a reference laboratory. 

Owner Melanie Williams (Williams1)
Last reviewed 24.12.2025
Next review 24.12.2026 (OK)