Tests:Digoxin, Plasma: Difference between revisions

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Tests:Digoxin, Plasma
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== Comments ==
== Comments ==
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| colspan="2" |Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay.  
| colspan="2" |Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay causing false elevated values.  


Heterophilic antibodies have been shown to interact with immunoglobulin reagents in some immunoassay systems.   
Heterophilic antibodies have been shown to interact with immunoglobulin reagents in some immunoassay systems.   

Latest revision as of 20:13, 14 September 2026

Overview

Department Biochemistry
Test Code DIG
Synonyms Digitalis 
Availability Monday - Sunday, testing routinely available out of hours
Turnaround Time 1 – 5hrs 
Stability – Add test 8 hours

Specimen Requirements

Specimen Serum

Plasma

Preferred 6 mL Red-Top
Acceptable 6 mL Li-Hep Green-Top
Unacceptable
Specimen Transportation
Paediatric Requirements Li-Heparin Microtainer

Aliquot Requirements

Sample Serum

Plasma

Preferred Volume 500 µL 
Minimum Volume 200 µL 
Aliquot Transportation

Clinical Information

Reference Intervals Range 0.6 - 2.0 nmol/L

Toxic levels >2.0 nmol/L 

Test Method Abbott Alinity Ci, Particle-enhanced turbidimetric inhibition immunoassay (PETINIA) 
Advanced Notice Not required 
Patient Preparation Samples are best taken at the trough, just before the next dose, or at least 8-12 hours post-dose, to avoid falsely high results due to delayed drug distribution after the dose. 

Comments

Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay causing false elevated values.

Heterophilic antibodies have been shown to interact with immunoglobulin reagents in some immunoassay systems. 

Owner Clair Crossley (Crossley1)
Last reviewed 14.09.2026
Next review 14.09.2027 (OK)