Tests:Creatinine Plasma: Difference between revisions

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Created page with "{{DISPLAYTITLE: Creatinine, Plasma}} Full Test List Biochemistry Tests {| class="wikitable" ! colspan="2" | ===''Overview''=== |- |Department |Biochemistry  |- |Test Code |PCRN |- |Synonyms |CRN, plasma |- |Turnaround Time |1 hour urgent - 2 hours routine  |- |Stability – Add test |24 Hours |- ! colspan="2" | ===''Specimen Requirements''=== |- |Specimen Type |Serum Plasma |- |Specimen Transportation | |- |Preferred |6 mL Plain <span style="background:#e..."
 
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{| class="wikitable"
{| class="wikitable"
! colspan="2" |
! colspan="2" |
===''Overview''===
==Overview==
|-
|-
|Department
|Department
|Biochemistry 
|Biochemistry 
|-
|-
|Test Code
|Test Code  
|PCRN
|PCRN
|-
|-
|Synonyms
|Synonyms
|CRN, plasma
|CRN, plasma
|-
|Test Avaiability
|Monday - Sunday, testing routinely available out of hours
|-
|-
|Turnaround Time
|Turnaround Time
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|-
|-
|Stability – Add test
|Stability – Add test
|24 Hours
|24 hours
|-
|-
! colspan="2" |
! colspan="2" |
===''Specimen Requirements''===
==Specimen Requirements==
|-
|-
|Specimen Type
|Specimen Type
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Plasma
Plasma
|-
|Specimen Transportation
|
|-
|-
|Preferred
|Preferred
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|Acceptable
|Acceptable
|4 mL Li-Heparin <span style="background:#3cb371"> Green-Top </span>   
|4 mL Li-Heparin <span style="background:#3cb371"> Green-Top </span>   
|-
|Specimen Transportation
|
|-
|-
|Pediatric Requirements
|Pediatric Requirements
|<span style="background:#99e6b3"> Li-Hep Microtainer </span> microtainer tube 600 µL  
|600 µL  <span style="background:#99e6b3"> Li-Heparin Microtainer </span>
|-
|-
! colspan="2" |
! colspan="2" |
===''Aliquot Requirements''===
==Aliquot Requirements ==
|-
|-
|Sample Type
|Sample Type
|Plasma  
| Plasma  
Serum
Serum
|-
|Preferred Volume
|100 µL
|-
|-
|Minimum Volume
|Minimum Volume
|100 µL
|
|-
|-
|Aliquot Transportation
|Aliquot Transportation
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|-
|-
! colspan="2" |
! colspan="2" |
===''Clinical Information''===
==Clinical Information==
|-
|-
|Reference Intervals
|Reference Intervals  
|   
|   
{| class="wikitable"
{| class="wikitable"
|Creatinine µmol/L
| Creatinine µmol/L
|
|
|-
|-
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|-
|-
|>2 yrs - 4  yrs ,
|>2 yrs - 4  yrs ,
|20 - 60
| 20 - 60  
|-
|-
|>4 yrs -  6yrs
|>4 yrs -  6yrs
|25 - 65
|25 - 65  
|-
|-
|>6 yrs -  10yrs
| >6 yrs -  10yrs
|25 - 70
|25 - 70
|-
|-
|>10 yrs -  15 yrs
|>10 yrs -  15 yrs  
|40 -  80
|40 -  80
|-
|-
|Male >15yr  + Adult
|Male >15yr  + Adult
|50 -  110    
|50 -  110  
|-
|-
|Female >15 yr + Adult
| Female >15 yr + Adult
|45 - 90
|45 - 90
|}
|}
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Reference range: 80 - 120 mL/min/1.73 m2  
Reference range: 80 - 120 mL/min/1.73 m2  


'''''Female'''''  
'''''Female'''''  
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Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.  
Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.  


'''''Male'''''   
'''''Male'''''   
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Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.  
Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.  


''<br />Children < 16 years- no calculation done''  
'''''Children''' < 16 years- no calculation done''  


'''''Interpretation'''''  
'''''Interpretation'''''  
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GFR declines by 1 ml/min/year over 40 years.
GFR declines by 1 ml/min/year over 40 years.
|-
|-
|Test Method
| Test Method
|Classical Jaffe Reaction using Abbott reagents on the  Abbott ci8200 analyser.   
|Classical Jaffe Reaction using Abbott reagents on the  Abbott ci8200 analyser.   


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|-
|-
! colspan="2" |
! colspan="2" |
===''Comments''===
==Comments==
|-
|-
| colspan="2" |
| colspan="2" |
|}
|}

Revision as of 12:50, 14 March 2025

Overview

Department Biochemistry 
Test Code PCRN
Synonyms CRN, plasma
Test Avaiability Monday - Sunday, testing routinely available out of hours
Turnaround Time 1 hour urgent - 2 hours routine 
Stability – Add test 24 hours

Specimen Requirements

Specimen Type Serum

Plasma

Preferred 6 mL Plain Red-Top
Acceptable 4 mL Li-Heparin Green-Top  
Specimen Transportation
Pediatric Requirements 600 µL   Li-Heparin Microtainer

Aliquot Requirements

Sample Type Plasma

Serum

Preferred Volume 100 µL
Minimum Volume
Aliquot Transportation

Clinical Information

Reference Intervals  
Creatinine µmol/L
0 - 1 mth 20 - 60  
>1 mth - 2 yr 20 - 50
>2 yrs - 4 yrs , 20 - 60
>4 yrs - 6yrs 25 - 65
>6 yrs - 10yrs 25 - 70
>10 yrs - 15 yrs 40 -  80
Male >15yr + Adult 50 -  110  
Female >15 yr + Adult 45 - 90

CKD-EPI calculation for eGFR

Reference range: 80 - 120 mL/min/1.73 m2


Female

Crn ≤62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-0.329 x [0.993] Age.

Crn >62 eGFR (ml/min) = 144 x [Crn(µmol/L)/0.7]-1.209 x [0.993] Age.

Male 

Crn ≤80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]-0.411 x [0.993] Age.

Crn >80 eGFR (ml/min) = 141 x [Crn(µmol/L)/0.9]- 1.209 x [0.993] Age.

Children < 16 years- no calculation done


Interpretation

Estimated GFR is only reliable under steady state conditions (stable Creatinine >4 days).

Caution should be used in interpretation in non-Caucasians, extremes of body weight, pregnancy, oedematous subjects, low Creatinine (<0.06mmol/L) and other complex cases.

GFR declines by 1 ml/min/year over 40 years.

Test Method Classical Jaffe Reaction using Abbott reagents on the Abbott ci8200 analyser. 

eGFR routinely reported on all valid samples.  Calculated using the plasma creatinine and CKD-EPI calculation.

Advanced Notice Not required  
Patient Preparation Not required

Comments

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