Tests:Urate, Plasma: Difference between revisions

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Created page with "{{DISPLAYTITLE: Urate, Plasma}} Full Test List Biochemistry Tests {| class="wikitable" ! colspan="2" | === ''Overview'' === |- |Department |Biochemistry |- |Test Code |PURT |- |Synonyms |Uric acid |- |Turnaround Time |2 hrs |- |Stability – Add test | |- ! colspan="2" | === ''Specimen Requirements'' === |- |Specimen Type |Plasma Serum |- |Specimen Transportation | |- |Preferred |6 mL Plain <span style="background:#e30022"> Red-Top</span> |-..."
 
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{| class="wikitable"
{| class="wikitable"
! colspan="2" |
! colspan="2" |
=== ''Overview'' ===
== Overview ==
|-
|-
|Department  
|Department  
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|Synonyms  
|Synonyms  
|Uric acid  
|Uric acid  
|-
|Test Availability
|Monday - Sunday, testing routinely available out of hours
|-
|-
|Turnaround Time  
|Turnaround Time  
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|-
|-
! colspan="2" |
! colspan="2" |
=== ''Specimen Requirements'' ===
== Specimen Requirements ==
|-
|-
|Specimen Type  
|Specimen Type  
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Serum
Serum
|-
|Specimen Transportation
|
|-
|-
|Preferred  
|Preferred  
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|Acceptable  
|Acceptable  
|4 mL Li-Hep  <span style="background:#3cb371"> Green-Top </span>  
|4 mL Li-Hep  <span style="background:#3cb371"> Green-Top </span>  
|-
|Unacceptable
|
|-
|Specimen Transportation
|
|-
|-
|Paediatric Requirements    
|Paediatric Requirements    
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|-
|-
! colspan="2" |
! colspan="2" |
=== ''Aliquot Requirements'' ===
== Aliquot Requirements ==
|-
|-
|Sample Type  
|Sample Type  
|
|-
|preferred Volume
|
|
|-
|-
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|-
|-
! colspan="2" |
! colspan="2" |
=== ''Clinical Information'' ===
== Clinical Information ==
|-
|-
|Reference Intervals  
|Reference Intervals  
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|-
! colspan="2" |
! colspan="2" |
=== ''Comments'' ===
== Comments ==
|-
|-
| colspan="2" |Changes with the reference range may be significant in pregnancy.  
| colspan="2" |Changes with the reference range may be significant in pregnancy.  
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The risk of developing gout is three times greater if the plasma urate levels are consistently above 0.42 mmol/L.  
The risk of developing gout is three times greater if the plasma urate levels are consistently above 0.42 mmol/L.  


Plasma urate levels often fall during an acute attack so a normal plasma urate does NOT exclude the diagnosis of gout at this time.  
Plasma urate levels often fall during an acute attack, so a normal plasma urate does NOT exclude the diagnosis of gout at this time.  


A raised plasma urate level is not sufficient to make the diagnosis of gout, which requires:  
A raised plasma urate level is not sufficient to make the diagnosis of gout, which requires:  

Revision as of 11:18, 18 March 2025

Overview

Department Biochemistry
Test Code PURT
Synonyms Uric acid
Test Availability Monday - Sunday, testing routinely available out of hours
Turnaround Time 2 hrs
Stability – Add test

Specimen Requirements

Specimen Type Plasma

Serum

Preferred 6 mL Plain Red-Top
Acceptable 4 mL Li-Hep Green-Top
Unacceptable
Specimen Transportation
Paediatric Requirements   600 µL Li-Hep Microtainer

Aliquot Requirements

Sample Type
preferred Volume
Minimum Volume
Aliquot Transportation

Clinical Information

Reference Intervals 0 – 11 years              0.08 - 0.34 mmol/L  

Male                         0.20 - 0.42 mmol/L

Female                      0.15 - 0.36 mmol/L

Test Method Ci8200 analyser, Abbott, Enzymatic.
Advanced Notice
Patient Preparation

Comments

Changes with the reference range may be significant in pregnancy.  

The risk of gout (and probability of diagnosis) is low if the plasma urate levels are repeatedly below 0.42 mmol/L.  

The risk of developing gout is three times greater if the plasma urate levels are consistently above 0.42 mmol/L.  

Plasma urate levels often fall during an acute attack, so a normal plasma urate does NOT exclude the diagnosis of gout at this time.  

A raised plasma urate level is not sufficient to make the diagnosis of gout, which requires:  

1. Classical history of podagra;  

2. Identification of urate crystals in joint fluid; or (in late cases), typical x-ray changes