Digoxin, Plasma
Tests:Digoxin, Plasma
Overview | |
|---|---|
| Department | Biochemistry |
| Test Code | DIG |
| Synonyms | Digitalis |
| Availability | Monday - Sunday, testing routinely available out of hours |
| Turnaround Time | 1 – 5hrs |
| Stability – Add test | 8 hours |
Specimen Requirements | |
| Specimen | Serum
Plasma |
| Preferred | 6 mL Red-Top |
| Acceptable | 6 mL Li-Hep Green-Top |
| Unacceptable | |
| Specimen Transportation | |
| Paediatric Requirements | Li-Heparin Microtainer |
Aliquot Requirements | |
| Sample | Serum
Plasma |
| Preferred Volume | 500 µL |
| Minimum Volume | 200 µL |
| Aliquot Transportation | |
Clinical Information | |
| Reference Intervals | Range 0.6 - 2.0 nmol/L
Toxic levels >2.0 nmol/L |
| Test Method | Abbott Alinity c series analyser using Abbott reagents. Particle-enhanced turbidimetric inhibition immunoassay (PETINIA) |
| Advanced Notice | Not required |
| Patient Preparation | Samples are best taken at the trough, just before the next dose, or at least 8-12 hours post-dose, to avoid falsely high results due to delayed drug distribution after the dose. |
Comments | |
| Specimens from patients treated with Digoxin immune FAB (Digibind) should be viewed with caution, as this substance is known to inhibit the assay causing false elevated values.
Heterophilic antibodies have been shown to interact with immunoglobulin reagents in some immunoassay systems. | |
| Owner | Clair Crossley (Crossley1) |
|---|---|
| Last reviewed | 23.09.2026 |
| Next review | 23.09.2027 (OK) |